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Rescue of alpha-synuclein toxicity in a yeast model of Parkinson's disease

Alliance of Genome Resources2026-08-01 收录

帕金森病酵母模型

α-突触核蛋白毒性

数据链接：

https://www.yeastgenome.org/dataset/GSE11633 数据链接链接失效反馈

官方服务：

资源简介：

Cellular toxicities of alpha-synuclein manifest through multiple pathways, including mitochondrial dysfunction and the inhibition of vesicle trafficking

应用场景：

神经退行性疾病模型

α-突触核蛋白毒性

Parkinson’s disease (PD) is one of the most common neurodegenerative diseases, which is characterized by progressive motor dysfunction as well as non-motor symptoms. Pathological and genetic studies h

NIAID Data Ecosystem50

OW949 zgIs125[P(dat-1)::alpha-Synuclein::YFP] | 2014-03-23T18:08:37+01:00

线虫行为表型分析

α-突触核蛋白毒性

This experiment is part of the C.elegans behavioural database. For more information and the complete collection of experiments visit http://movement.openworm.org preview link : https://www.youtub

NIAID Data Ecosystem20

OW949 zgIs125[P(dat-1)::alpha-Synuclein::YFP] | 2014-03-14T09:03:41+01:00

线虫行为表型分析

α-突触核蛋白毒性

This experiment is part of the C.elegans behavioural database. For more information and the complete collection of experiments visit http://movement.openworm.org preview link : https://www.youtub

NIAID Data Ecosystem10

Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by extracellular alpha-synuclein

α-突触核蛋白毒性

神经退行性分子机制

MES cells were treated with vehicle or 250 nM extracellular alpha-synuclein and plasma membrane proteins were labeled with biotin, followed by affinity purification. The biotinylated enriched membrano

NIAID Data Ecosystem30

Additional file 1: of Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of Îą-synuclein toxicity

基因型分型

α-突触核蛋白毒性

Markers used in the genotyping of the Îą-synuclein ILs. (XLSX 22 kb)

NIAID Data Ecosystem20