Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form)

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein Authors: Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D. Deposit date: 2022-04-12 Release date: 2022-04-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.769 Å) Cite: A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint. Iscience, 26, 2023

嗜热毛壳菌（Chaetomium thermophilum）来源的UDP-葡萄糖糖蛋白葡萄糖基转移酶（UDP-Glucose Glycoprotein Glucosyltransferase）催化结构域（脱辅基形式，apo form）。描述组分：2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰胺基-2-脱氧-β-D-吡喃葡萄糖、钙离子、UDP-葡萄糖-糖蛋白葡萄糖基转移酶样蛋白。作者：Roversi P、Zitzmann N、Bayo Y、Le Cornu J.D.。存档日期：2022-04-12；发布日期：2022-04-20；最后修改日期：2024-11-13。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.769埃）。引用文献：《UGGT（内质网糖蛋白折叠质量质控检查点）的喹啉-8-醇类亚毫摩尔级抑制剂》，《Iscience》，2023年，第26卷。