Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP

Protein Data Bank Japan2024-02-21 更新2026-03-21 收录

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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP Descriptor: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase) Authors: Wittmann, J, Rudolph, M. Deposit date: 2007-06-19 Release date: 2007-11-06 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008

人尿苷单磷酸合酶（UMP synthase）的乳清苷-5'-单磷酸脱羧酶结构域（Asp312Asn突变体）与OMP（乳清苷-5'-单磷酸，Orotidine-5'-monophosphate）结合的晶体结构描述项：甘油、乳清苷-5'-单磷酸、尿苷5'-单磷酸合酶（UMP synthase）作者：Wittmann J、Rudolph M. 存入日期：2007-06-19 发布日期：2007-11-06 最后更新日期：2024-02-21 实验方法：X射线衍射（1.85埃）引用文献：人类乳清苷-5'-单磷酸脱羧酶的结构支持共价催化机制并为药物设计提供框架，《Structure》，第16卷，2008年

创建时间：

2007-06-19