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This study investigates if DNA methylation is involved in defense against disease in social spider
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创建时间：
2024-07-05
相关数据集
Genome-wide map of DNA methylation to unravel the function of EBF1 C-terminus domain. Mus musculus
To study the function of the C-terminus domain, DNA methylation status was profiled in Empty, Ebf1wt and Ebf1DC transduced Ebf1-/- progenitor cells. Overall design: Freshly prepared Ebf1−/− c-Kit+ fet
NIAID Data Ecosystem70
De novo methylaton of the unmethylated K. phaffii genome by human DNA methyltransferases (DNMTs) [RNA-seq]
We engineered combinatorial knock-in of human DNMTs in Komagataella phaffii, a yeast species lacking endogenous DNA methylation, to characterize methylation preferences and functional consequences of
NIAID Data Ecosystem50
Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltansferase with CRISPR/dCas9
Although associations between DNA methylation and gene expression were established four decades ago, the causal role of DNA methylation in gene expression remains unresolved. Different strategies to a
NIAID Data Ecosystem30
Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs).. Methylation and gene expression data obtained from Dnmt3b+/+, Dnmt3bD/D and Dnmt3bCI/CI MYC induced T-cell lymphomas (MTCLs).
DNA methylation has suppressive effects on gene transcription and it is involved in a variety of physiologic processes, including development and cancer. As we and others demonstrated, Dnmt3b is a tum
NIAID Data Ecosystem60
Comparison of bulk RNAseq results of WT and TKO E14 NPCs. Comparison of bulk RNAseq results of WT and TKO E14 NPCs
We investigate the impact of DNA methylation on neural somatic differentiation. To this end, we used in vitro neural progenitor cell (NPC) differentiation on WT and DNA-methylation free TKO murine ESC
NIAID Data Ecosystem40
