Effects of StcE treatment on in vitro brain endothelial cell line bEnd.3

Mucin-domain glycoproteins populate the brain endothelial cell surface, but their roles as a class of glycoconjugates are largely unknown. Here, we perform bulk RNA-sequencing of bEnd.3 cells treated with StcE, which enzymatically degrades cell surface mucins, in order to understand the effects of mucin removal on brain endothelial cell function. Bulk RNA-sequencing of bEnd.3 cells treated with StcE or saline in growth media