Parental dietary exposure to polycyclic aromatic hydrocarbons (PAHs) - F1 survival
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This dataset is comprised of toxicological assays testing the influence of the dietary exposure to polycyclic aromatic hydrocarbons (PAHs) of a parental generation (P0), on the survival of its offspring when exposure to the same compounds were performed on the embryo and larval life stages. Five separate groups composed of adult female and male zebrafish (Danio rerio) were used for this experiment. The first group was fed with flake control-food; the second group was fed with flake food previously spiked with water; and the rest of the groups were fed with flake food previously spiked with High Energy Water Accommodated Fractions - HEWAF (10%, 50%, 100%). The parental generation was measured and weighted during the exposure, and its F1 generation was exposed via the water to the same compounds. Endpoints for this experiment were changes in body length or weight of the PO and survival of the F1 when the exposures were performed. Data of both generations are provided in a spreadsheet containing some graphs; the statistical analysis and plots were made in SigmaPlot 12 (files are included), photos and videos taken from both generations are also included.
本数据集涵盖一系列毒理学试验,旨在探究亲代(P0)经膳食暴露于多环芳烃(polycyclic aromatic hydrocarbons, PAHs)后,对其子代在胚胎及幼体生命阶段暴露于相同化合物时的存活率所产生的影响。本试验共设置5组成年雌雄斑马鱼(Danio rerio):第一组投喂普通片状对照饲料;第二组投喂预先掺加水的片状饲料;其余三组分别投喂预先掺加了10%、50%、100%高能量水可分配馏分(High Energy Water Accommodated Fractions, HEWAF)的片状饲料。亲代在暴露期间接受体长测量与体重称重,其子一代(F1)则通过水体暴露于相同受试化合物。本试验的观测终点为亲代(P0)的体长、体重变化,以及F1在暴露过程中的存活率。两代斑马鱼的相关数据存储于包含部分图表的电子表格中;统计分析与绘图均通过SigmaPlot 12完成(配套文件已提供),同时还收录了两代样本的拍摄照片与视频素材。



