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Lung SORT LNPs Enable Precise Homology-Directed Repair Mediated CRISPR/Cas Genome Correction in Cystic Fibrosis Models

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NIAID Data Ecosystem2026-05-01 收录
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This study used Next Generation Sequencing (NGS) to detect gene correction efficiencies in mouse whole lungs after intravenous injections of DOTAP40 lipid nanoparticles encapulating Cas9/sgG542X/HDR template in CF G542X mice.

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2023-09-04
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