Supplementary Material for: Human Amniotic Membrane (hAM) graft in the management of Peripheral Hypertrophic Subepithelial Corneal Degeneration – A case report

Abstract:

Introduction:
In this report, we describe the case of Peripheral Hypertrophic Subepithelial Corneal Degeneration (PHSCD), managed with surgical excision and a human amniotic membrane (hAM) graft. In this article, we also propose a table for differential diagnosis, which might help physicians recognize this uncommon clinical entity in practice.

Case presentation:
A 45-year-old female Caucasian patient presented with decreased vision, itching and burning in both eyes, and a presence of pseudopterygium in the right eye, causing visual decline. Routine ocular exams an Anterior Segment OCT led to the diagnosis of PHSCD, after a careful differential diagnosis with other similar clinical occurrences. Subsequently, the patient was successfully managed with surgical intervention and an amniotic membrane graft placement.

Conclusion:
PHSCD is a rare disease, which in advanced cases can be successfully managed with hAM graft. No recurrence of the lesions was observed at one-year follow-up in our patient.