Crystal structure of the inactive form of GalNAc-T2 in complex with the glycopeptide MUC5AC-Cys13

Crystal structure of the inactive form of GalNAc-T2 in complex with the glycopeptide MUC5AC-Cys13 Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUCIN, ... Authors: Lira-Navarrete, E, delasRivas, M, Companon, I, Pallares, M.C, Kong, Y, Iglesias-Fernandez, J, Bernardes, G.J.L, Peregrina, J.M, Rovira, C, Bernado, P, Bruscolini, P, Clausen, H, Lostao, A, Corzana, F, Hurtado-Guerrero, R. Deposit date: 2015-02-26 Release date: 2015-03-11 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation. Nat.Commun., 6, 2015

N-乙酰半乳糖胺基转移酶2（GalNAc-T2）非活性形式与糖肽MUC5AC-Cys13结合的晶体结构。组分描述：1,2-乙二醇（1,2-ETHANEDIOL）、2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖（2-acetamido-2-deoxy-alpha-D-galactopyranose）、黏蛋白（MUCIN）等。作者：Lira-Navarrete, E、delasRivas, M、Companon, I、Pallares, M.C、Kong, Y、Iglesias-Fernandez, J、Bernardes, G.J.L、Peregrina, J.M、Rovira, C、Bernado, P、Bruscolini, P、Clausen, H、Lostao, A、Corzana, F、Hurtado-Guerrero, R。沉积日期：2015-02-26；发布日期：2015-03-11；最后修改日期：2024-11-06。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.67埃（Å）。引用文献：《GalNAc-转移酶催化域与凝集素域的动态互作调控蛋白质O-糖基化》（Dynamic Interplay between Catalytic and Lectin Domains of Galnac-Transferases Modulates Protein O-Glycosylation），《自然-通讯》（Nat.Commun.），第6卷，2015年