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Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... Authors: Jalali-Yazdi, F, Chowdhury, S, Yoshioka, C, Gouaux, E. Deposit date: 2018-09-30 Release date: 2018-11-28 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (6.23 Å) Cite: Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175, 2018

本数据集所表征的样品为处于‘2-Knuckle-Symmetric’构象的异二聚体NMDA受体(NMDA receptor)GluN1/GluN2A,该受体与甘氨酸、谷氨酸形成复合物,反应体系中添加1毫摩尔浓度的乙二胺四乙酸(EDTA),且pH值为7.4。 描述项:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、离子型谷氨酸受体(Glutamate receptor ionotropic)…… 作者:Jalali-Yazdi, F、Chowdhury, S、Yoshioka, C、Gouaux, E. 沉积日期:2018-09-30 发布日期:2018-11-28 末次修改日期:2024-11-20 实验方法:电子显微镜(分辨率6.23埃) 引用文献:《锌与质子对GluN1/GluN2A型NMDA受体的抑制机制》,《细胞》(Cell),第175卷,2018年
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2018-09-30
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