The Molecular Architecture of Cationic Lipid Nanoparticles for siRNA Delivery

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The proposal aims to use SANS and contrast variation to determine the detailed molecular architecture of lipid nanoparticles (LNPs) containing the nucleic acid, siRNA. The...

The Molecular Architecture of Cationic Lipid Nanoparticles for siRNA Delivery

The proposal aims to use SANS and contrast variation to determine the detailed molecular architecture of lipid nanoparticles (LNPs) containing the nucleic acid, siRNA. The information thus gained will

DataCite Commons2020-07-30 更新40

Molecular Architecture of Lipid Nanoparticles using SANS

Lipid nanoparticles (LNPs) are composed of a mixture of a cationic ionisable lipid, distearoylphosphatidylcholine (DSPC), cholesterol, and a PEG-lipid. Significantly, LNPs are increasingly being inves

DataCite Commons2025-07-09 更新70

Data for: "Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection"

Self-amplifying RNA (SAM) represents a versatile tool that can be used to develop potent vaccines, potentially able to elicit strong antigen-specific humoral and cellular-mediated immune responses to

DataCite Commons2020-07-09 更新40

The Molecular Architecture of Cationic Lipid Nanoparticles for siRNA Delivery

DataCite Commons2020-07-30 更新20

Molecular Architecture of Lipid Nanoparticles using SANS

DataCite Commons2025-07-09 更新20