Effect of treatment OPM2 multiple myeloma cells with EPA, DHA or bortezomib

ChEBI2022-06-26 更新2026-07-12 收录

多发性骨髓瘤治疗

抗癌药物筛选

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11907 数据链接链接失效反馈

官方服务：

资源简介：

Effect of treatment OPM2 multiple myeloma cells with EPA, DHA or bortezomib

创建时间：

2022-06-26

DataSheet1_Discovery of novel anti-tumor compounds targeting PARP-1 with induction of autophagy through in silico and in vitro screening.docx

PARP-1靶向药物发现

抗癌药物筛选

Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective

NIAID Data Ecosystem50

NCI60 Transcriptome

抗癌药物筛选

癌细胞分析

MRNA sequencing of the NCI60 cell lines

NIAID Data Ecosystem40

Thiazolation of phenylthiosemicarbazone to access new thiazoles: anticancer activity and molecular docking

抗癌药物筛选

分子对接

Aim: Novel thiazole hybrids were synthesized via thiazolation of 4-phenylthiosemicarbazone (4). Materials & methods: The anticancer activity against the NCI 60 cancer cell line panel. Results: Methyl

NIAID Data Ecosystem10

Discovery of Quinazoline-2,4(1 H ,3 H )‑dione Derivatives Containing 3‑Substituted Piperizines as Potent PARP-1/2 InhibitorsDesign, Synthesis, In Vivo Antitumor Activity, and X‑ray Crystal Structure Analysis

PARP抑制剂研发

抗癌药物筛选

Inhibiting PARP-1/2 offered an important arsenal for cancer treatments via interfering with DNA repair of cancer cells. Novel PARP-1/2 inhibitors were designed by capitalizing on methyl- or ethyl-subs

NIAID Data Ecosystem50

Transcriptome data of cancerous (HCT-116) and non-cancerous (IPEC-J2) intestinal cells treated with curcumin analogues

抗癌药物筛选

转录组分析

This dataset contains RNA sequencing data of cancerous HCT-116 and non-cancerous intestinal IPEC-J2 cells treated with curcumin, three curcumin-based benzothiazepane analogues, and untreated controls.

NIAID Data Ecosystem10

Effect of treatment OPM2 multiple myeloma cells with EPA, DHA or bortezomib

资源简介：

相关数据集