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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy [human_FOXO1_TCF7_OE_RNAseq]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE263162
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Investigating the transcriptional profile of human FOXO1 or TCF7 overexpressing α-lewisY CAR T cells Human anti-Lewis Y CAR T cells overexpressing mCherry (control), FOXO1 or TCF7 were generated from healthy donor peripheral blood mononuclear cells (PBMC). Control, FOXO1 or TCF7 overexpressing CD8+ CAR T cells were assessed by RNA-Sequencing
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2024-05-08
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