官方服务：
资源简介：
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景：
创建时间：
2019-03-27
相关数据集
Castration-induced SPARC down-regulation in stroma cells drives neuroendocrine differentiation of prostate cancer
Fatal neuroendocrine (NE) prostate cancer evolves from castration-resistant adenocarcinoma as a mechanism of resistance to androgen deprivation/anti androgen receptor therapies. Evidence suggests the
NIAID Data Ecosystem80
Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer [scATAC-seq]. Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer [scATAC-seq]
Neuroendocrine prostate cancer (NEPC) arises primarily through neuroendocrine transdifferentiation (NEtD) as an adaptive mechanism of therapeutic resistance. Models to define the functional effects of
NIAID Data Ecosystem30
Lineage specific chromatin modification guides Pax5 mediated gene expression in neuroendocrine like differentiation of prostate cancer (ATAC-Seq). Lineage specific chromatin modification guides Pax5 mediated gene expression in neuroendocrine like differentiation of prostate cancer (ATAC-Seq)
Neuroendocrine-like differentiation of castration-resistant prostate cancer is highly aggressive and independent of the androgen receptor signaling for its progression. During such lineage differentia
NIAID Data Ecosystem20
AmpliSeq Transcriptome Analysis of Human Prostate Cancer Cells With or Without Overt SRRM4 Expression
Prostate adenocarcinoma (AdPC) cells can undergo lineage switching to neuroendocrine cells and develop into therapy-resistant neuroendocrine prostate cancer (NEPC). While genomic/epigenetic alteration
NIAID Data Ecosystem20
