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Lactococcus lactis as a Cell Factory for High-Level Diacetyl Production

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PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC92266/
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资源简介:
We report the engineering of Lactococcus lactis for the efficient conversion of sugar into diacetyl by combining NADH-oxidase overproduction and α-acetolactate decarboxylase inactivation. Eighty percent of the carbon flux was found to be rerouted via α-acetolactate to the production of diacetyl by preloading the cells with NADH-oxidase before their use as a cell factory.
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American Society for Microbiology (ASM)
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