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TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

ChEBI2015-02-26 更新2026-07-21 收录

上皮-间质转化调控

肿瘤转移抑制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-58560 数据链接链接失效反馈

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TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

应用场景：

创建时间：

2015-02-26

上皮-间质转化调控

染色质可及性分析

TGFβ cytokines have crucial roles in development, proliferation, tissue homeostasis, differentiation, and immune regulation. Consequently, alterations in TGFβ signaling underlie numerous diseases, inc

NIAID Data Ecosystem90

Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.

上皮-间质转化调控

转录因子功能分析

We have identified the transcription factor forkhead box protein F2 (Foxf2) to be upregulated in its expression during the EMT process and studied its functional contribution to EMT by siRNA-mediated

NIAID Data Ecosystem60

Identification of Ovol2 binding regions in HC11 cells. Mus musculus

上皮-间质转化调控

乳腺发育与癌症

Epithelial cells possess remarkable plasticity, having the ability to become mesenchymal cells through alterations in adhesion and motility (epithelial-to-mesenchymal transition or EMT). Recent studie

NIAID Data Ecosystem50

Spatial Transcriptional Profile of the Chick and Mouse Endocardial Cushions Identify Novel Regulators of Endocardial EMT in vitro. Spatial Transcriptional Profile of the Chick and Mouse Endocardial Cushions Identify Novel Regulators of Endocardial EMT in vitro

发育生物学

上皮-间质转化调控

Objective: We developed an unbiased strategy to identify genes important in endocardial epithelial-to-mesenchymal transformation (EMT) using a spatial transcriptional profile. Methods and Results: End

NIAID Data Ecosystem60

Figure S1 - Restoration of miR-1228* Expression Suppresses Epithelial-Mesenchymal Transition in Gastric Cancer

癌症分子机制

上皮-间质转化调控

Effect of miR-1228* on EMT in AGS cells. (A) Western blot analysis of epithelial marker E-cadherin and mesenchymal marker Vimentin in miR-1228* stable transfected AGS cells and control. (B) Transwell

NIAID Data Ecosystem50

TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis

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