Telomeric repeats facilitate CENP-A incorporation via telomere binding proteins

ChEBI2013-08-22 更新2026-07-21 收录

着丝粒表观遗传

端粒蛋白功能

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-46427 数据链接链接失效反馈

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Telomeric repeats facilitate CENP-A incorporation via telomere binding proteins

创建时间：

2013-08-22

RNA-Seq in senescent cells with restored levels of TRF2

衰老转录组学

端粒蛋白功能

Cellular senescence is accompanied by profound changes in telomere and heterochromatin structure that contribute to ageing. Telomere shortening is a key driver of replicative senescence that activate

NIAID Data Ecosystem50

Pot-1::mCherry transgene images from: Gametes deficient for Pot1 telomere binding proteins alter levels of telomeric foci for multiple generations

端粒蛋白功能

转基因线虫成像

These images are raw data associated with the figures for the Communications Biolgoy manuscript \"Gametes deficient for Pot1 telomere binding proteins alter levels of telomeric foci for multiple gener

DataONE2021-02-04 更新50

Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

端粒蛋白功能

基因组稳定性

Genomic rearrangements (gross chromosomal rearrangements, GCRs) threatens genome integrity and cause cell death or tumor formation. At the terminus of linear chromosomes, a telomere-binding protein co

Figshare2019-08-27 更新40

Human centromere repositioning activates transcription and opens chromatin fibre structure [Agilent 'open' chromatin-chip]

染色质构象

着丝粒表观遗传

This study was designed to investigate the chromatin structure of human centromeres. Human centromeres appear as constrictions on mitotic chromosomes and form a platform for kinetochore assembly in mi

NIAID Data Ecosystem50

Differential requirement for functional telomeres in neurons

端粒蛋白功能

基因表达调控

RNAseq was perfomed in control and TRF2-DCVX-cre mice to evaluate the effect of telomere dysfunction in gene expression in neurons Hippocampus and Contex of 3 months old mice were isolated to perform

NIAID Data Ecosystem40

Telomeric repeats facilitate CENP-A incorporation via telomere binding proteins

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