Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4uym
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole Descriptor: 14-ALPHA STEROL DEMETHYLASE, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole Authors: Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. Deposit date: 2014-09-02 Release date: 2015-08-19 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structure-Functional Characterization of Cytochrome P450 Sterol Alpha-Demethylase (Cyp51B) from Aspergillus Fumigatus and Molecular Basis for the Development of Antifungal Drugs J.Biol.Chem., 290, 2015
致病性丝状真菌烟曲霉（Aspergillus fumigatus）来源的甾醇14-α去甲基酶（sterol 14-alpha demethylase, CYP51B）与伏立康唑（voriconazole）结合的晶体结构
描述项：14-α甾醇去甲基酶、含Fe的原卟啉IX、伏立康唑
作者：Hargrove, T.Y.、Wawrzak, Z.、Lepesheva, G.I.
提交日期：2014-09-02
发布日期：2015-08-19
最后修改日期：2024-01-10
实验方法：X射线衍射（2.55 Å）
引用文献：《烟曲霉细胞色素P450甾醇α-去甲基酶（Cyp51B）的结构功能表征及抗真菌药物开发的分子基础》，J. Biol. Chem.，290卷，2015年
创建时间：
2014-09-02
