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Palladium Catalyzed Insertion Reaction of Isocyanides with 3‑Arylisoxazol-5(4<i>H</i>)‑ones: Synthesis of 4‑Aminomethylidene Isoxazolone Derivates

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资源简介:

A palladium catalyzed insert reaction of isocyanides to 3-arylisoxazol-5­(4H)-ones for the construction of 4-aminomethylidene isoxazolone derivates is reported. In this transformation, only the C–H bond of the methylene group was involved while the remaining ring structure was retained. In general, this work provided a new protocol for the synthesis of 4-aminomethylidene isoxazolones.

创建时间:
2019-08-13
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