The small intestine has a robust regenerative capacity, and various cell types serve as âcells-of-originâ in the epithelial regeneration process after injury. However, how much each population con
Age-related tissue alterations have been associated with a decline in stem cell number and function. Increased cell-to-cell variability in transcription or epigenetic marks has been proposed to be a m
Tissue homeostasis requires long-term lineage fidelity of somatic stem cells. Whether and how age-related changes in somatic stem cells impact the faithful execution of lineage decisions remains large
