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Acute kidney injury (AKI) is a rapid decline in kidney function caused by various factors. It is characterized by a decrease in glomerular filtration rate, leading to water and sodium retention, electrolyte imbalances, and systemic symptoms affecting multiple body systems. Cardiac surgery with cardiopulmonary bypass is a common cause of AKI. Previous studies have suggested that the harm caused by CPB to the human body includes systemic inflammatory reactions, hemodilution, and nonpulsatile perfusion[1]. Depending on the evaluation criteria used, the probability of AKI after cardiac surgery ranges from 20% to 40%[2]. Despite years of research, acute kidney injury following cardiac surgery remains a significant problem. Identifying the risk factors for kidney injury is crucial in order to implement targeted strategies.