Effect of external nutrient levels on synergistic killing.
收藏NIAID Data Ecosystem2026-03-09 收录
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(A) Isobologram for ISG-21 and PRT-1 interactions in PGIM. Note that synergistic action is lost in this medium. (B) Isobologram for an identical growth experiments after increasing the culture medium isoleucine concentration to 34 μM, showing restored synergy. The ISG-21 IC50 values in (A) and (B)—17.3 ± 1 nM and 1.25 ± 0.1 μM, x axis intercepts—differ markedly because extracellular nutrient levels affect killing by primary component blockers.
创建时间：
2016-03-16
