Human inner ear transcriptome RNA-seq dataset (cochlea and vestibular tissues) from Schrauwen et al., Hearing Research 2016

DescriptionThis dataset contains RNA-seq transcriptome data from adult human inner ear tissues originally reported in:
Schrauwen I. et al., A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear. Hearing Research. 2016;333:266–274. doi:10.1016/j.heares.2015.08.013.
The original study performed transcriptomic profiling of the adult human inner ear, including the cochlea, ampulla, saccule, and utricle, obtained from individuals without hearing impairment. RNA-sequencing analysis quantified expression for more than 50,000 predicted genes corresponding to approximately 200,000 transcripts, enabling identification of genes preferentially expressed in inner ear tissues and characterization of coding and non-coding RNA species involved in auditory and vestibular function.
The dataset provides a high-resolution catalogue of gene expression across human inner ear tissues and has been used to investigate:
genes preferentially expressed in the cochlea or vestibular organsexpression patterns of known hearing-loss geneslong non-coding RNAs and pseudogenestranscripts subject to nonsense-mediated decaycandidate genes within unmapped non-syndromic deafness lociIn the original publication, these data were made available through a supplementary website hosted by the Translational Genomics Research Institute (TGen). However, the original download link is no longer active.
To ensure long-term accessibility and reproducibility, the dataset has been archived here.
Data originData were generated and first described in:
Schrauwen I. et al. (2016)
A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear
Hearing Research 333:266–274
https://doi.org/10.1016/j.heares.2015.08.013
Reason for repository depositionThe dataset was previously distributed through a project webpage that is no longer accessible. This repository entry preserves the dataset to ensure continued public availability and reproducibility of analyses that use this resource.
CitationIf you use this dataset, please cite the original publication:
Schrauwen I. et al. Hearing Research 2016;333:266–274.
NotesThis dataset is provided for data preservation and accessibility purposes. All credit for the dataset generation belongs to the authors of the original study