Correlation Between MRI Findings of Pituitary Gland and Prolactin Level Among Hyperprolactinemia Adult Female Saudi Patients in Rural Areas: A Retrospective Multicentric Study

A retrospective multicentric study including 4 regions (Alkarj, Afif, Najran, and Riyadh) from western Saudia Arabia between July 2020 and September 2023 including 168 female patients with abnormal prolactin levels who underwent brain MRI for the pituitary gland evaluation. The study excluded patients who had a pacemaker, aneurysm clip, orbital metallic foreign body, prior pituitary disease, severe renal insufficiency, liver cirrhosis, uncompensated primary hypothyroidism, and females on hyperprolactinemic drugs. The correlation between hyperprolactinemia and MRI findings was investigated and analyzed. A receiver operating characteristic (ROC) curve analysis was utilized to determine a serum prolactin threshold value for diagnosing pituitary adenoma in hyperprolactinemic individuals.