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Transcriptome-wide analysis of the effects of systematic knock down of splicing factors and regulators using siRNAs in HeLa cells

ChEBI2024-10-21 更新2026-07-12 收录

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数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11202 数据链接链接失效反馈

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资源简介：

Transcriptome-wide analysis of the effects of systematic knock down of splicing factors and regulators using siRNAs in HeLa cells

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创建时间：

2024-10-21

RNA剪接调控

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Although mutations in DNA are the best-studied source of neoantigens that determine response to immune checkpoint blockade, alterations in RNA splicing within cancer cells could similarly result in ne

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ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing

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ELAV/Hu factors are conserved RNA binding proteins that play diverse roles in mRNA processing and regulation. The founding member, Drosophila Elav, was recognized as a vital neural factor 35 years ago

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Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency [RNA-Seq]

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Nuclear speckles, a type of membraneless nuclear organelle in higher eukaryotic cells, play a vital role in gene expression regulation. Using the reverse transcription-based RBP binding sites sequenci

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The impact of Prp18p on splicing fidelity and efficiency in budding yeast

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Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

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Glucose dissociates DDX21 dimers to regulate mRNA processing and promote epidermal differentiation (RNA-Seq II)

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Glucose is an important cellular energy source, however, glucose's function as a second messenger remains relatively unexplored. Here, we find that glucose binds directly to DDX21 to regulate its func

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Transcriptome-wide analysis of the effects of systematic knock down of splicing factors and regulators using siRNAs in HeLa cells

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