Cross-linking mass spectrometry of synapses purified from mouse brain

NIAID Data Ecosystem2026-03-12 收录

突触蛋白质组学

交联质谱

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https://www.omicsdi.org/dataset/pride/PXD015160 数据链接链接失效反馈

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资源简介：

cross-linking experiments of three biologically independent replicates of hippocampal synaptosomes.

创建时间：

2020-12-03

4D-diaXLMS: Proteome-wide Four-Dimensional Data-Independent Acquisition Workflow for Cross-linking Mass Spectrometry

交联质谱

数据独立采集

Cross-linking Mass Spectrometry (XL-MS) is a powerful tool for examining protein structures and interactions. Nevertheless, anal-ysis of low-abundance cross-linked peptides is often limited in data-de

国家人口健康科学数据中心120

Identification of MS-Cleavable and Non-Cleavable Chemically Crosslinked Peptides with MetaMorpheus

交联质谱

蛋白质结构解析

The present work describes a novel search program for the detection of both MS-cleavable and non-cleavable crosslinked peptides and it is the first software program reported with both capacities. The

NIAID Data Ecosystem50

Hybrid structural modeling of protein-RNA complexes using crosslinking of segmentally isotope labeled RNA and tandem mass spectrometry

蛋白质-RNA复合物结构

交联质谱

To study protein-RNA interactions at single amino acid and single nucleotide resolution we developed a new approach, termed cross-linking of segmentally isotope labeled RNA and tandem mass spectrometr

NIAID Data Ecosystem40

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

蛋白质复合物结构解析

交联质谱

The 26S proteasome is the macromolecular machine responsible for ATP/ubiquitin dependent degradation. As aberration in proteasomal degradation has been implicated in many human diseases, structural an

NIAID Data Ecosystem60

Developmental dynamics of the postsynaptic proteome to understand synaptic maturation and dysmaturation

突触蛋白质组学

发育疾病分子机制

The postsynaptic density (PSD) is a protein condensate composed of ~1,000 proteins beneath the postsynaptic membrane of excitatory synapses. The number, shape, and plasticity of synapses are altered d

NIAID Data Ecosystem40

Cross-linking mass spectrometry of synapses purified from mouse brain

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