Total Syntheses of Cladoacetals A and B: Confirmation of Absolute Configurations
收藏数据链接：
官方服务：
资源简介：
The first enantioselective syntheses of cladoacetals A (1a, overall yield: 16%) and B (1b, overall yield: 34%) from crotonaldehyde in nine and seven steps, respectively, have been accomplished. Sharpless asymmetric dihydroxylation, Suzuki coupling, and acid-catalyzed intramolecular acetalization were the key steps in the syntheses. The absolute configuration of natural (+)-cladoacetal A was affirmed to be 1S,3S,4R, whereas that of (−)-cladoacetal B was affirmed to be 1R,3S,4S.
创建时间：
2016-02-20
