Asexual growth kinetics and male to female gametocyte ratios.

Asexual growth kinetics (A) Mice (n = 5) were inoculated with 105 parasites i.v and parasitemia (percent infected erythrocytes) is expressed as Mean ± SD. Asexual parasitemias between WT and KO were compared by regression analysis and they were not statistically significant (p = 0.71). (B) Male to female gametocyte ratios of PbDmc1 KO parasites compared to WT parasites when mosquito transmission experiments were done. Gametocytes were counted per 1000 rbc and data shown is from two independent experiments, N is the total number of gametocytes analyzed. Male to female ratios between WT and KO were compared using the Fisher’s exact test and they were not statistically significant (p = 0.99) for both experiments.