PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P04F03 from the F2X-Universal Library

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P04F03 from the F2X-Universal Library Descriptor: A1 cistron-splicing factor AAR2, N-methyl-2-{[2-(methylamino)-2-oxoethyl]amino}benzamide, Pre-mRNA-splicing factor 8 Authors: Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. Deposit date: 2022-08-26 Release date: 2022-11-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022

PanDDA分析小组提交的存档数据集：Aar2/RNaseH与F2X-通用文库（F2X-Universal Library）片段P04F03形成的复合物结构。描述：A1顺式剪接因子AAR2、N-甲基-2-{[2-(甲氨基)-2-氧代乙基]氨基}苯甲酰胺、前mRNA剪接因子8。作者：Barthel, T、Wollenhaupt, J、Lima, G.M.A、Wahl, M.C、Weiss, M.S. 存档日期：2022-08-26；发布日期：2022-11-02；最后修改日期：2024-05-22。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.55埃（Å）。引用文献：《大规模晶体学片段筛选加速化合物优化并鉴定潜在蛋白质-蛋白质相互作用位点》，《药物化学杂志》（J.Med.Chem.），第65卷，2022年。