Summary of the SHANK protein functions and of the main findings obtained for patients with ASD.
收藏Figshare2015-12-02 更新2026-04-29 收录
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The frequency of mutation in patients and control individuals was calculated from the total cohort (Table 1). The frequency of mutation in patients with normal IQ (IQ>70) and low IQ (IQ70 = 1 638 & nASD with IQ70 = 354 and nASD with IQ70 = 335 & nASD with IQ70 = 667 & nASD with IQde novo mutations. The black star indicates that Schmeisser et al. (2012) [21] found an increase in NMDA currents, while Won et al. (2012) [22] found a decrease in NMDA currents in two independent SHANK2 knock-out mice.Summary of the SHANK protein functions and of the main findings obtained for patients with ASD.
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2015-12-02
