Transcriptome sequencing of Spodoptera frugiperda larvae upon plumbagin exposure

Plumbagin, 5-hydroxy-2-methyl-1,4-naphthoquinone (C11H8O3), is an important secondary metabolite and bioactive compound in plants originally isolated from the medicinal plant Plumbago zeylanica and has been reported to exhibit potent larvicidal activity against several insect pests. Transcriptomic changes of S. frugiperda after plumbagin treatment were investigated to elucidate the underlying molecular mechanism of its insecticidal activity.