X-ray crystal structure of AmpC WT beta-lactamase in complex with covalently bound imipenem

X-ray crystal structure of AmpC WT beta-lactamase in complex with covalently bound imipenem Descriptor: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, beta-lactamase Authors: Beadle, B.M, Shoichet, B.K. Deposit date: 2002-04-26 Release date: 2002-11-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural Basis for Imipenem Inhibition of Class C beta-lactamases ANTIMICROB.AGENTS CHEMOTHER., 46, 2002

本数据集为AmpC野生型β-内酰胺酶（AmpC WT beta-lactamase）与共价结合的亚胺培南（imipenem）形成复合物的X射线晶体结构。结构描述符：(5R)-5-[(1S,2R)-1-甲酰基-2-羟丙基]-3-[(2-{[(E)-亚胺甲基]氨基}乙基)硫烷基]-4,5-二氢-1H-吡咯-2-羧酸。作者：Beadle, B.M.、Shoichet, B.K.。提交日期：2002-04-26；发布日期：2002-11-27；最后修改日期：2024-11-20。实验方法：X射线衍射（1.8埃（Å））。引用文献：《亚胺培南抑制C类β-内酰胺酶的结构基础》，刊载于《抗微生物剂与化疗》（ANTIMICROB.AGENTS CHEMOTHER.），第46卷，2002年。