For each missense variant used in our analysis, shows the PDB identification code, mutation site, pathogenicity (disease or neutral), and active sites. Sites are aligned to the associated PDB file. (
Predicting the functional consequences of single point mutations has relevance to protein function annotation and to clinical analysis/diagnosis. We developed and tested Packpred that makes use of a m
Leptospira weilii belongs to the pathogenic Leptospira group and is a causal agent of human and animal leptospirosis in many world regions. L. weilii can produce varied clinical presentations from asy