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Treatment with antidepressant drugs in a rat model of Traumatic Brain Injury

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115614
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Microarray analysis was performed to look at the mRNA and miRNA profiles of several antidepressant drugs in the rat hippocampus after Traumatic Brain Injury to test the hypothesis that antidepressant drugs ameliorate gene and miRNA dysregulation after TBI. Rats received either a Sham injury or TBI injury. Certain groups of rats that received a TBI were injected one hour after injury with one of the following antidepressent drugs: Prozac, Zoloft, or Imipramine. Rats were survived for 24 hours and then hippocampus dissected out, stored in RNA later and sent to GenUs Biosystems for miRNA mircoarray analysis.
创建时间:
2019-09-11
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