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Enantioselective Acylation of Silyl Ketene Acetals through Fluoride Anion-Binding Catalysis

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Enantioselective_Acylation_of_Silyl_Ketene_Acetals_through_Fluoride_Anion_Binding_Catalysis/2616778
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A highly enantioselective acylation of silyl ketene acetals with acyl fluorides has been developed to generate useful α,α-disubstituted butyrolactone products. This transformation is promoted by a new thiourea catalyst and 4-pyrrolidinopyridine and represents the first example of enantioselective thiourea anion-binding catalysis with fluoride.
创建时间:
2011-09-07
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