CRISPR_Cas9_screens_for_drug_resistance_in_AML_cell_lines
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https://www.ncbi.nlm.nih.gov/sra/ERP008475
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资源简介：
Acute myeloid leukaemia (AML) continues to have a very high mortality and its treatment has not changed for more than 20 years. Here, we propose to apply genomic-wide screens to directly identify therapeutic vulnerabilities of AML using AML cells lines with pre-defined somatic mutations. Our studies will be based on genome-wide CRISPR/CAs9 gRNA screens and will be used to identify drivers of drug resistance to standard chemotherapies.
创建时间：
2021-02-04
