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The high-throughput DICER cleavage assays on 23296 shRNA variants

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NIAID Data Ecosystem2026-03-13 收录
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The high-throughput DICER cleavage assays were conducted shRNA variants containing different sequences. We showcase a comprehensive cleavage activity of DICER on different shRNAs containing different secondary structures. 23296 shRNA variants were processed by DICER in vitro. The original substrates and cleaved products were cloned and sequenced.

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2022-05-05
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