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Estrogen Receptor Regulated Gene Signatures in Invasive Breast Cancer Cells and Aggressive Breast Tumors

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174189
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When co-activated with IKKβ, estrogen receptor regulates a subset of genes in invasive cells, which are associated with proliferation, vesicle and intracellular trafficking. These genes are associated with poor survival in patients and are enriched in metastatic tumors in PDX models. scRNA-seq (OneCellBio) and bulk RNA-seq
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2022-06-30
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