TRANSCRIPTIONAL REGULATION DIRECTED USING SYNTHETIC OF TRANSCRIPTION FACTORS
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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The present relates to are the directed regulation of the gene expression and， more specifically， to factors of synthetic transcription (ORDERING) that comprise less one to the domain of Recognition designed highly specific for the target and that comprising in addition to the less one of activation or silencing domain for modulating the expression of one gene of interest， Preferably for modulating the transcription of one gene morfogénico of one eukaryotic organism. Also， disclosed are methods which utilize the ORDERING for improving the frequency of transformation， for optimizing the successful approaches edition of the genome， for Providing haploid or double haploid organisms and/or for providing compositions suitable for the general transformation， but also for purposes of playback. Claim 2: factor of The synthetic transcription of the claim 1， where in the to the less one of activation domain is， or is one fragment， of an Molecule selected from the group that consists in to the less one SUCH effector， to the less one CRISPR system/disarmed， nuclease to the less one of finger domain of zinc， And to the less one homing endonuclease disarmed， or any combination of the same.
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
