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The Regulation of Lysosomal TRPML1 Channels on Insulin Secretion raw data.7z

NIAID Data Ecosystem2026-05-02 收录

数据链接：

https://figshare.com/articles/dataset/The_Regulation_of_Lysosomal_TRPML1_Channels_on_Insulin_Secretion_raw_data_7z/29243660 数据链接链接失效反馈

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The Regulation of Lysosomal TRPML1 Channels on Insulin Secretion raw data.

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创建时间：

2025-06-05

胰岛素分泌调节

药物筛选与作用机制

Reported effects on basal (BIS) and glucose stimulated (GSIS) insulin secretion, and the primary targets via which the compounds exert their effects are given, together with the expected control funct

Figshare2015-12-02 更新60

Inhibition of MGL reduced GSIS in INS-1 cells and isolated rat islets.

胰岛素分泌调节

糖尿病机制

(A) JZL184 dose-dependently reduced GSIS during static incubations in INS-1 cells (n = 3). (B) JZL184 (10 μM) reduced GSIS in INS-1 cells regardless of the temporal exposure (n = 3). (C) INS-1 cells d

Figshare2016-03-16 更新20

Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells

胰岛素分泌调节

受体信号通路

The insulin-like growth factor II (IGF-II)/mannose-6-phosphate (M-6-P) receptor is known to participate in endocytosis as well as sorting of lysosomal enzymes and is involved in membrane trafficking t

PubMed Central1997-06-10 更新00

The Transcriptional Co-Regulator HCF-1 Is Required for INS-1 β-cell Glucose-Stimulated Insulin Secretion

细胞功能

胰岛素分泌调节

The transcriptional co-regulator host cell factor-1 (HCF-1) plays critical roles in promoting cell cycle progression in diverse cell types, and in maintaining self-renewal of embryonic stem cells, but

Figshare2016-01-18 更新40

Modulation of insulin secretion through RBFOX2-mediated alternative splicing [RNA-seq MIN6]

胰岛素分泌调节

RNA剪接

Recent studies have identified dysregulation of RNA-binding proteins (RBPs) and aberrant mRNA splicing in the onset of diseases including diabetes. Here we investigated the role of RBFOX2 in the pancr

NIAID Data Ecosystem00

The Regulation of Lysosomal TRPML1 Channels on Insulin Secretion raw data.7z

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