Group deposition of ZIKV NS2B-NS3 protease in complex with inhibitors from ASAP Discovery Consortium -- Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0029804-001

Group deposition of ZIKV NS2B-NS3 protease in complex with inhibitors from ASAP Discovery Consortium -- Crystal Structure of ZIKV NS2B-NS3 protease in complex with ASAP-0029804-001 Descriptor: (2R)-2-(6-chloro-1H-indazol-4-yl)-N-methyl-2-[(3-oxo-1,3-dihydro-2-benzofuran-5-yl)amino]acetamide, DIMETHYL SULFOXIDE, Serine protease NS3, ... Authors: Ni, X, Marples, P.G, Godoy, A.S, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Fairhead, M, Lithgo, R.M, Lee, A, Kenton, N, Thompson, W, Tomlinson, C.W.E, Wild, C, Winokan, M, Williams, E.P, Chandran, A.V, Walsh, M.A, Fearon, D, von Delft, F. Deposit date: 2025-04-10 Release date: 2025-04-23 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.292 Å) Cite: Group deposition of ZIKV NS2B-NS3 protease in complex with inhibitors from ASAP Discovery Consortium To Be Published

ASAP发现联盟(ASAP Discovery Consortium)寨卡病毒(ZIKV) NS2B-NS3蛋白酶-抑制剂复合物集体提交数据集——寨卡病毒(ZIKV) NS2B-NS3蛋白酶与ASAP-0029804-001复合物的晶体结构
描述物：(2R)-2-(6-氯-1H-吲唑-4-基)-N-甲基-2-[(3-氧代-1,3-二氢-2-苯并呋喃-5-基)氨基]乙酰胺、二甲基亚砜、丝氨酸蛋白酶NS3……
作者：Ni X、Marples P.G、Godoy A.S、Koekemoer L、Aschenbrenner J.C、Balcomb B.H、Fairhead M、Lithgo R.M、Lee A、Kenton N、Thompson W、Tomlinson C.W.E、Wild C、Winokan M、Williams E.P、Chandran A.V、Walsh M.A、Fearon D、von Delft F
提交日期：2025-04-10
发布日期：2025-04-23
最后修改日期：2026-02-18
实验方法：X射线衍射（分辨率2.292埃）
引用说明：ASAP发现联盟来源的寨卡病毒NS2B-NS3蛋白酶-抑制剂复合物集体提交数据集，待发表