The distribution of connectors and the topological roles of the modules among the AD, aMCI and NC groups.

Values in the “Regions” column are the region number within each module. The “Connector” column represents the numbers of connector nodes (C and H) in each module and its ratio regarding to the total number of regions in such module. The values in the “Intermodule” column indicate the numbers of intermodule edges and its ratio to the total number of intermodule connections in all modules. Bold date indicates the module with both the higher connector coefficient (>0.6) and the higher intermodule connections (>1/number of modules) [19].