Estimated allele frequencies of potential novel variants in ACE2 with predicted Spike binding phenotypes.
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The estimate is calculated from the observed occurrence of rare variants in ACE2 in gnomAD [24] (6.1 × 10−6) and the proportion of SNPs at the 25 residues that are predicted to modify Spike affinity at different thresholds (see Methods).
创建时间:
2022-03-02



