The GU-ECG Database: ECG Datasets for Detection and Classification of Acute Myocardial Ischaemia Through Machine Learning

Gazi University ECG (GU-ECG) database is a set of ECG data acquired from 74 coronary artery disease patients with severe stenosis (>70%) in at least one coronary artery who had symptoms of chest pain and were planned to undergo elective percutaneous transluminal coronary angioplasty (PTCA) at Department of Cardiology, Faculty of Medicine, Gazi University. It is constructed as a result of a clinical research study performed to investigate morphological anomalies in ECG signals that occur during complete coronary artery occlusion caused by PTCA, which reduces myocardial blood flow and induces acute myocardial ischaemia (AMI), leading to significant changes in ST segment and T wave of ECG [1,2]. Before PTCA, 12-lead pre-inflation ECG recordings were continuously acquired prior to catheter insertion to coronary artery at cardiac catheterization laboratory. During PTCA, 12-lead inflation ECG recordings that started during balloon dilatation, then continued throughout balloon inflation period in a major coronary artery were continuously acquired from all patients. In order to achieve optimal angiographic and clinical results of PTCA, balloon was inflated for at least 60 sec. in each patient and it was deflated either due to the occurrence of chest pain, cardiac arrhythmia, hypotension, or after a maximum inflation time of 300 sec. After PTCA, 12-lead post-inflation ECG recordings were continuously acquired at least 180 sec. after balloon deflation in coronary artery at catheterization laboratory. A portable continuous 12-lead ECG device (microCOR, Infron Ltd), which amplifies, digitizes, processes and transmits data wirelessly to its software via a USB adapter in digital format, was used for data acquisition [3]. Recordings were digitized at a sampling rate of 8800 Hz with 24-bit sampling resolution and 0.1 µV amplitude resolution to produce high-resolution digital signals. Time instants related to balloon inflation and deflation during PTCA, occluded coronary artery in which PTCA is performed and patient's history of previous myocardial infarction were annotated by experienced cardiologists to facilitate the development and performance evaluation of various signal processing and artificial intelligence techniques that will utilize the GU-ECG database [4,5,6,7]. Only patients receiving elective PTCA in one of major coronary arteries were included in the database, whereas patients who had atrial fibrillation, ventricular tachycardia, paced rhythm, or myocardial infarction during data acquisition were excluded. 12-lead pre-inflation, inflation, and post-inflation ECG recordings of each patient are included in experiment data files section with file extension *.ekg, which is data format of microCOR ECG device. Computer software which receives data from ECG device, displays, saves, and exports it to different file formats is included in experiment data files section with file extension *.exe, which is executable file format of microCOR PC software.加济亚大学心电图（Gazi University ECG, GU-ECG）数据库收录了74例冠心病患者的心电图数据，这些患者至少存在一支冠状动脉狭窄程度≥70%，伴有胸痛症状，且计划在加济亚大学医学院心内科接受择期经皮冠状动脉腔内成形术（percutaneous transluminal coronary angioplasty, PTCA）。本数据集源自一项临床研究，旨在探究PTCA引发的完全性冠状动脉闭塞期间心电图信号的形态异常——该闭塞会减少心肌血流量，诱发急性心肌缺血（acute myocardial ischaemia, AMI），进而导致心电图ST段与T波出现显著改变[1,2]。PTCA术前，在心脏导管室中，于冠状动脉导管插入前持续采集12导联预扩张心电图记录。PTCA术中，对所有患者持续采集12导联扩张期心电图记录：该记录始于球囊扩张时刻，并在主要冠状动脉的球囊扩张全程持续采集。为获得PTCA最佳的血管造影与临床效果，每位患者的球囊扩张时长至少为60秒，球囊可因胸痛、心律失常、低血压发作而放气撤除，或在最长扩张时长达300秒时撤除。PTCA术后，在心脏导管室中，于冠状动脉球囊放气后至少180秒时持续采集12导联后扩张期心电图记录。本数据集采用便携式连续12导联心电图设备（microCOR，Infron有限公司）进行数据采集，该设备可放大、数字化、处理数据，并以数字格式通过USB适配器将数据无线传输至配套软件[3]。记录以8800 Hz的采样率进行数字化，采样分辨率为24位，幅度分辨率达0.1 µV，从而生成高分辨率数字信号。经验丰富的心内科医师对以下信息进行了标注：PTCA术中球囊扩张与放气的时刻、接受PTCA的闭塞冠状动脉、患者既往心肌梗死病史，以助力基于GU-ECG数据库的各类信号处理与人工智能技术的开发与性能评估[4,5,6,7]。本数据集仅纳入在单支主要冠状动脉接受择期PTCA的患者，而排除在数据采集期间存在心房颤动、室性心动过速、起搏心律或心肌梗死的患者。每位患者的12导联预扩张期、扩张期与后扩张期心电图记录均收录于实验数据文件模块，文件扩展名为*.ekg，该格式为microCOR心电图设备的专用数据格式。配套软件可接收心电图设备的数据，实现数据显示、存储与多格式导出，其可执行文件格式为*.exe，收录于实验数据文件模块。