SMARCAD1-mediated active replication fork stability maintains genome integrity

NIAID Data Ecosystem2026-05-10 收录

复制叉蛋白质组学

基因组稳定性

数据链接：

https://data.mendeley.com/datasets/2p7dx6mt9b 数据链接链接失效反馈

官方服务：

资源简介：

This is the iPOND-SILAC-MS datasets used in Figure 1A.

创建时间：

2025-11-11

Histone H3.3 maintains genome integrity during mammalian development

表观遗传调控

基因组稳定性

Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans, and has been implicated in many important biological processes including cell differentiation and reprogramming. Germlin

NIAID Data Ecosystem80

MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stability

基因组稳定性

转录调控机制

Raw data for Huang et al.,

NIAID Data Ecosystem50

BLM prevents instability of structure-forming DNA sequences at common fragile sites

基因组稳定性

DNA修复

Genome instability often arises at common fragile sites (CFSs) leading to cancer-associated chromosomal rearrangements. However, the underlying mechanisms of how CFS protection is achieved is not well

Figshare2018-12-11 更新50

SIRT7 tethering of L1 elements to the nuclear lamina mediates their transcriptional repression

基因组稳定性

表观遗传调控

Long interspersed elements-1 (LINE-1, L1) are retrotransposons that hold the capacity of selfpropagation in the genome with potential mutagenic outcomes. How somatic cells restrict L1 activity and how

干细胞与再生医学数据中心2022-02-20 更新70

TDP-43 safeguards the embryo genome from L1 retrotransposition. TDP-43 safeguards the embryo genome from L1 retrotransposition

逆转录转座子抑制剂

基因组稳定性

We report that TAR DNA binding protein 43 (TDP-43), mutations in which constitute a major risk factor for amyotrophic lateral sclerosis (ALS), inhibits L1 retrotransposition in mouse embryonic stem ce

NIAID Data Ecosystem50

SMARCAD1-mediated active replication fork stability maintains genome integrity

资源简介：

相关数据集