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Epigenomic analysis of Parkinson's disease neurons identifies TET2 loss as neuroprotective

NIAID Data Ecosystem2026-05-01 收录

帕金森病表观基因组

TET2

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE136010 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-10-19

平滑肌细胞表观遗传学

TET2

Epigenetic control of lineage-specific gene expression is essential for cell differentiation, acquisition of specialized functions, and tissue homeostasis. Here, we uncovered a unique epigenetic pathw

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TET2-mediated deprogramming of breast cancer cells

乳腺癌表观遗传重编程

TET2

Methylation and demethylation of cytosines in DNA are believed to act as keystones of cell-specific gene expression through controlling chromatin structure and accessibility to transcription factors.

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RNA mass spectrometry of tRNAs after incubation with recombinant TET2

RNA图谱

TET2

Mass spectrometry on purified tRNA after incubation with recombinant TET2 catalytic fragment or control reactions. As shown in Fig. 4F of "TET2 chemically modifies tRNAs and regulates tRNA fragment le

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datasheet2_Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro.docx

代谢相关脂肪肝病治疗

TET2

Background: Metabolic associated fatty liver disease (MAFLD), characterized by hepatic lipid accumulation and fatty degeneration, is intertwined with obesity and type 2 diabetes mellitus (T2DM). Empag

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TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.. TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.

肥大细胞分化

TET2

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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