How many replicates of arrays are required to detect gene expression changes in microarray experiments? A mixture model approach

Background It has been recognized that replicates of arrays (or spots) may be necessary for reliably detecting differentially expressed genes in microarray...研究背景：学界已普遍认可，在基因芯片（microarray）实验中，为可靠检测差异表达基因（differentially expressed genes），采用阵列（或探针点）的重复设置或许是必要的。