The time-dependent response of placental trophoblast stem cells to hyperosmolar stress. Mus musculus

Stress induces undifferentiated stem cells to differentiate in a way that looks like normal differentiation We used hyperosmolar stress as a generic, energy-depleting stressor and tested for the global changes in the transcriptional response of placental trophoblast stem cells Keywords: Time course for stressed stem cells to assay for differentiative and homeostatic responses Overall design: Placental trophoblast stem cells were subjected to 0, 0.5, 2, 6, and 24 hours of hyperosmolar stress and then assayed by Affymetrix 430MOE V2 whole mouse genome arrays.