Additional file 4 of A recurrent de novo missense mutation in COL1A1 causes osteogenesis imperfecta type II and preterm delivery in Normande cattle

Additional file 4: Figure S1. Electropherograms of selected individuals for a 40-bp segment encompassing the COL1A1 candidate variant. Electropherograms of an affected calf, a control half-sib carrying the at-risk haplotype in its ancestral version (i.e., without the mutation), and their sire Ly. The region displayed ranges from positions 36,473,946 to 36,473,985 bp on BTA19. The position of the candidate substitution is highlighted in red; *Note the low proportion of allele A versus G in Ly supporting germline mosaicism.