Case-control meta-analysis of cohort I^a and cohort II^b in a total of 712 SLE cases and 1131 controls.

a Uppsala, Stockholm, Lund, n = 567 cases, n = 512 controls. b Linköping, n = 145 cases, n = 619 controls. c WHO class III or IV on renal biopsy, according to the 1995 WHO classification system [2]. Biopsies available in 178 patients. d Glomerular filtration rate <30 mL/min/1.73 m2[22]. Data available for 225 patients. e Unadjusted combined p-value and OR calculated using Cochran-Mantel Haenszel chi-square test. P-values remaining significant after Bonferroni correction for 4 tested SNPs are in italic. f Adjusted p-value and OR from meta-analysis of logistic regression results including age and gender as covariates. Number of cases and controls; lupus nephritis, n = 229, proliferative nephritis, n = 111, severe renal insufficiency, n = 31, SLE, n = 711, controls, n = 960.